Wayne Chang began coding at 7 on an Apple IIe and, by 11, launched a top-400 global website. As a teenager, he was involved with Napster during its early days, contributing to one of the first major peer-to-peer file-sharing platforms. As hacker "ttol," he created MyAdvantage (used by millions) and LanCraft (hacked Blizzard's Battle.net). He wrote nestea2.c, which exploited a vulnerability affecting most operating systems including Windows, Mac, Linux, and including hardware such as Cisco routers.

Chang also wrote installers for Razor 1911, the oldest software cracking group. His Quake 3 engine hacks led to sending source code to id Software's John Carmack, which ultimately improved the id Tech 3 engine.

Chang founded i2hub, a popular file-sharing network connecting over 400 universities via Internet2. With i2hub, he teamed up with the Winklevoss twins to form "The Winklevoss Chang Group," in its battle with early Facebook (depicted in The Social Network). Subsequently, Chang helped found Dropbox, and with Drew Houston, recruited co-founder Arash Ferdowsi, and with both Drew and Arash, pitched Dropbox to Paul Graham at Y Combinator.

He then co-founded multiple successful tech startups. Crashlytics, with Jeff Seibert, which was acquired by Twitter in its then-largest acquisition where he then served as GM of Twitter's developer platform. Crashlytics was acquired by Google from Twitter, and is now the leading mobile SDK installed and used on over 7 billion devices (monthly). He also co-founded Digits, an applied AI company valued at ~$600 million, and Patented.ai, his second applied AI company focused on high-stakes litigation tools. His latest startup is Reasoner, the reasoning engine for applications that demand the highest precision and accuracy.

Chang holds over 20 patents, including "Live Video Streaming", "API Manager", and "Feature Switching Kit." He was named to Boston Business Journal's 40 under 40 and received an honorary PhD from UMass Amherst. In 2016, he delivered the UMass Amherst Commencement Speech titled "Hack the System."